The effect of SLC6A6 Knock-down on bcCML leukemia

RNA sequencing analysis was performed on leukemia cells sorted from sex and age matched SLC6A6 WT and KO leukemic mice Spleen from mice transplanted with bcCML leukemia ( BCR-ABL and NUP98-HOXA9) were extracted .Leukemia cells were sorted and processed for RNA sequencing

本研究从移植了bcCML白血病（携带BCR-ABL与NUP98-HOXA9基因）的小鼠中提取脾脏组织，随后从性别与年龄匹配的SLC6A6野生型（wild type, WT）和敲除型（knockout, KO）白血病小鼠的脾脏中分选白血病细胞，对分选得到的细胞进行RNA测序（RNA sequencing）分析。