ID linking table for all samples that have been sequenced in the CRUK-ICGC Prostate Group projects

Prostate cancer somatic genomic sequencing data generated from 2011 onwards under auspices of the International Cancer Genome Consortium Prostate Cancer UK consortium (CRUK-ICGC Prostate Group), co-led by Colin Cooper and Ros Eeles, with other Principal Investigators (Brewer, Neal, Bova, McDermott, Wedge, Lynch, Massie, and Foster) and others as listed in study publications. Funded by Cancer Research UK and other funders as listed in study publications. Contents and publications related to each dataset are described with each dataset (EGAD) entry. Our study was funded with the ambition of collecting Whole Genome DNA sequence data from 250 prostate cancers, with matching transcriptome and methylome data. The original aims of the project were: 1. To understand the significance of multifocal prostate cancer. 2. To understand the clinical heterogeneity of prostate cancer to devise markers for predicting outcome and for drug targeting. 3. To understand the molecular basis of development and spread of castration-resistant and metastatic disease 4. To understand the aetiology of prostate cancer particularly the large variation in incidences that occur in different populations and ethnic groups. This table contains links between all the IDs, in particular between those that have been published in research articles and the The European Genome-phenome Archive (EGA) where the raw sequencing data is held (https://ega-archive.org/studies/EGAS00001000262).本数据集为2011年起在国际癌症基因组联盟（International Cancer Genome Consortium, ICGC）英国前列腺癌联盟（CRUK-ICGC前列腺癌工作组）支持下产生的前列腺癌体细胞基因组测序数据，由Colin Cooper与Ros Eeles联合牵头，其他首席研究员包括Brewer、Neal、Bova、McDermott、Wedge、Lynch、Massie及Foster，其余参与人员详见研究发表文献。本项目由英国癌症研究基金会（Cancer Research UK）及研究发表文献中列明的其他资助方共同资助。各数据集的相关内容与发表成果均在对应的EGAD条目中予以说明。本研究的资助初衷为收集250例前列腺癌的全基因组DNA测序数据，以及匹配的转录组与甲基化组数据。本项目的初始目标如下：1. 阐明多灶性前列腺癌的临床意义；2. 解析前列腺癌的临床异质性，以开发用于预测患者预后及指导药物靶向治疗的生物标志物；3. 阐明去势抵抗性前列腺癌与转移性前列腺癌的发生及进展的分子机制；4. 解析前列腺癌的发病病因，尤其是不同人群与种族间发病率存在显著差异的成因。本表格包含所有标识符之间的对应关系，尤其是已在研究论文中发表的标识符与存储原始测序数据的欧洲基因组-表型组档案馆（European Genome-phenome Archive, EGA）之间的关联，该档案馆的对应研究页面为：https://ega-archive.org/studies/EGAS00001000262。