Bats ORs and their ancestor ORs

We compare OR repertoire sizes across taxa and apply a new pipeline that integrates comparative genome data with protein structure modeling and then we employ molecular docking techniques with small molecules to analyze OR functionality based on binding energies.

本研究对不同类群的嗅觉受体（Olfactory Receptor, OR）基因家族规模开展比较分析，并采用一套整合了比较基因组数据与蛋白质结构建模的全新分析流程；随后，我们借助结合小分子的分子对接技术，基于结合能解析嗅觉受体的功能特性。