Austrian Crystallographic Diffraction Consortium

The Austrian Crystallographic Diffraction Consortium (ACDC) BAG aims at supporting several macromolecular structural biology groups across Austria (in total
20 research groups at 9 institutions in 4 cities). We employ mainly the technique of X-ray crystallography to characterize macromolecular biological complexes,
but also solution scattering approaches are frequently used to characterize dynamic assemblies. Approval of this BAG will be essential for researchers in all
our groups to carry out their structural studies on various health-related and basic research-oriented topics, which are targeted at characterizing large molecular
assemblies or proteins currently under-represented in the PDB, including membrane proteins. Corresponding high-resolution diffraction data are only obtainable
through the use of synchrotron radiation sources. Thus regular synchrotron access is highly desirable to maintain a competitive advantage in our individual
research fields

奥地利晶体衍射联盟（Austrian Crystallographic Diffraction Consortium, ACDC）BAG旨在为奥地利境内的大分子结构生物学研究团队提供支持，总计覆盖4座城市的9家科研机构，共计20个研究组。该小组主要采用X射线晶体学（X-ray crystallography）技术表征大分子生物复合物，同时也常借助溶液散射手段解析动态分子组装体的结构。该小组的获批对于所有研究组的科研人员开展相关结构研究至关重要：相关研究涵盖诸多健康相关及基础科研主题，目标为解析目前在蛋白质数据库（Protein Data Bank, PDB）中收录结构占比偏低的大型分子组装体与膜蛋白等蛋白质结构。此类高分辨率衍射数据仅可通过同步辐射光源获取，因此稳定的同步辐射光束使用权限对于各研究组在各自研究领域保持竞争优势而言不可或缺。