Genome-wide association study identifies two risk loci for tuberculosis in Han Chinese

We performed a multistage genome-wide association study on 2,949 pulmonary TB patients and 5,090 healthy controls (833 cases and 1,220 controls were genome-wide genotyped in discovery stage) from Han Chinese population. The summary data for the discovery stage from the published study is available in this site, as well as gwas.bio-x.cn and analysis.bio-x.cn/gwas, for download.<br><b><i>Data Download Agreement: </i><br><br>If you download these data, you and your immediate collaborators (“investigators”) acknowledge and agree to all of the following conditions: </b><br><br>&gt; These data are provided on an "AS-IS" basis, without warranty of any type, expressed or implied, including but not limited to any warranty as to their performance, merchantability, or fitness for any particular purpose;<br><br>&gt; Investigators will use these results for scientific research and educational use only;<br><br>&gt; Reposting or public distribution of these results files is prohibited;<br><br>&gt; Investigators certify that they are in compliance with all applicable local, state, and federal laws or regulations and institutional policies regarding human subjects and genetics research; <br><br>&gt; Investigators will cite the appropriate publication(s) in any communications or publications arising directly or indirectly from these data; <br><br>&gt; Investigators will never attempt to identify any participant. <br><br>&gt; Appropriate use of these data requires considerable attention to detail, prior experience, and technical skill. If investigators use these data, any and all consequences are entirely their responsibility.<br>

本研究针对汉族人群中的2949名肺结核（pulmonary TB）患者与5090名健康对照开展了多阶段全基因组关联研究（genome-wide association study），其中发现阶段共对833例病例及1220名健康对照进行全基因组基因分型。本研究已发表的发现阶段汇总数据可在本网站以及gwas.bio-x.cn、analysis.bio-x.cn/gwas平台获取下载。<br><b><i>数据下载协议：</i></b><br><br>若您下载本数据集，您及直接合作人员（以下统称“研究者”）须认可并同意以下全部条款：<br><br>&gt; 本数据集以“现状”形式提供，不提供任何明示或暗示的担保，包括但不限于关于数据集适用性、适销性或特定用途适配性的担保；<br><br>&gt; 研究者仅可将本数据集用于科学研究与学术教育用途；<br><br>&gt; 禁止对本数据集文件进行转发或公开分发；<br><br>&gt; 研究者须声明其已遵守所有与人类受试者研究及遗传学研究相关的现行地方、州级及联邦法律法规与机构政策；<br><br>&gt; 若因本数据集直接或间接产生任何交流或发表成果，研究者须引用本研究的相关已发表文献；<br><br>&gt; 研究者不得尝试识别任何研究参与者；<br><br>&gt; 本数据集的合规使用需要研究者具备细致的操作能力、相关研究经验与专业技术素养。若研究者使用本数据集，由此产生的全部后果均由其自行承担。