Comparison of serum leptin, glucose, total cholesterol and total protein levels in fertile and repeat breeder cows

In the present study we measured serum glucose, leptin, total cholesterol and total protein concentrations in repeat breeder cows and compared them with fertile cows. For this aim, 20 repeat breeder cows and 20 fertile cows were used as material. Repeat breeder cows were found to have lower levels of leptin and glucose as compared with fertile ones. No significant differences in total cholesterol and total protein levels were observed between the two groups. No significant correlation of leptin with glucose, total cholesterol and total protein was observed in fertile and repeat breeder cows. Low concentrations of glucose and leptin can have some effects on reproductive problems as repeat breeder and help to understand potential mechanisms impairing fertility in repeat breeder cows.

本研究检测了屡配不孕母牛（repeat breeder cows）的血清葡萄糖（serum glucose）、瘦素（Leptin）、总胆固醇（total cholesterol）与总蛋白（total protein）浓度，并与正常可育母牛（fertile cows）开展对比分析。本研究选取20头屡配不孕母牛与20头正常可育母牛作为实验材料。结果显示，相较于正常可育母牛，屡配不孕母牛的瘦素与血清葡萄糖水平更低；两组间的总胆固醇与总蛋白水平未观察到显著差异。在正常可育母牛与屡配不孕母牛群体中，均未发现瘦素与血清葡萄糖、总胆固醇及总蛋白之间存在显著相关性。血清葡萄糖与瘦素水平低下可能与屡配不孕的繁殖障碍存在关联，该结果有助于解析导致屡配不孕母牛生育能力受损的潜在分子机制。