Cholinesterase inhibition by rivastigmine in colon, plasma, and brain of DSS drinking treated mice.

Rivastigmine 0.5 or 1 = mice treated with rivastigmine (0.5 mg/kg or 1 mg/kg) once daily. Data represent percent ChE inhibition induced by rivastigmine compared to that in mice treated with PBS and drinking DSS. Data represent the mean ± SEM from 10 animals. Significantly different from value in mice treated with rivastigmine (0.5 mg/kg), **p<0.01.

0.5 mg/kg剂量组与1 mg/kg剂量组：指每日单次给予0.5 mg/kg或1 mg/kg利斯的明（Rivastigmine）处理的实验小鼠。本数据为利斯的明诱导的胆碱酯酶（ChE）活性抑制百分比，以经磷酸盐缓冲液（PBS）处理且饮用葡聚糖硫酸钠（DSS）的小鼠组为参照。数据结果为10只实验动物的均值±标准误（SEM）。与0.5 mg/kg利斯的明处理组小鼠的检测值相比，差异具有统计学显著性（**p<0.01）。