Ginsenoside compound K plays an anti-inflammatory effect without inducing glucose metabolism disorder in adjuvant-induced arthritis rats. Ginsenoside compound K plays an anti-inflammatory effect without inducing glucose metabolism disorder in adjuvant-induced arthritis rats

We studied hepatic mRNA expression levels in normal Wistar rats, adjuvant arthritic (AA) rats, and AA rats administered by gavage (ginsenoside CK or dexamethasone). The aim of the study was to determine the differences in the effects of ginsenoside CK and dexamethasone on hepatic mRNA levels in AA rats. The dexamethasone group may have a greater effect on mRNA in the liver. Overall design: We studied hepatic mRNA expression levels in normal Wistar rats, adjuvant arthritic (AA) rats, and AA rats administered by gavage (ginsenoside CK or dexamethasone).

本研究检测正常Wistar大鼠、佐剂性关节炎（adjuvant arthritic, AA）大鼠以及灌胃给予人参皂苷CK（ginsenoside CK）或地塞米松（dexamethasone）的AA大鼠的肝脏mRNA表达水平。本研究旨在明确人参皂苷CK与地塞米松对AA大鼠肝脏mRNA表达水平的影响差异。推测地塞米松组对大鼠肝脏mRNA的表达调控作用更为显著。实验整体设计：本研究检测正常Wistar大鼠、佐剂性关节炎（adjuvant arthritic, AA）大鼠以及灌胃给予人参皂苷CK或地塞米松的AA大鼠的肝脏mRNA表达水平。