Genome-wide analysis of the transcriptional profile of Zika virus-infected HepG2 cells

We report the identification of pathways upregulated by Zika virus infection in HepG2 cells 48 h post infection We obtained a list of diferentially expressed genes by comparing HepG2 cells infected with Zika virus (n=3 independent experiments) to mock-infected HepG2 cells (n=3 independent experiements). This list was later used for pathway overrepresentaion analysis.

本研究报道了寨卡病毒（Zika virus）感染HepG2细胞48小时后上调信号通路的鉴定结果。本研究通过对比寨卡病毒感染的HepG2细胞（n=3次独立实验）与假感染的HepG2细胞（n=3次独立实验），获得了差异表达基因（differentially expressed genes）列表。后续将该基因列表用于通路富集分析（pathway overrepresentation analysis）。