Exploring genome diversity of Termite and termitarium from Western ghats for novel anti-microbials. Exploring genome diversity of Termite and termitarium from Western ghats for novel anti-microbials

The rise of drug-resistant pathogens has become a critical global health concern, necessitating the search for alternative sources of antimicrobial agents. Conventional antibiotics are becoming increasingly ineffective, necessitating the search for novel sources of antimicrobial compounds. Termites and their associated termitarium have been identified as promising reservoirs of novel antimicrobial compounds due to their unique ecological interactions and evolutionary history. With a rich history of antimicrobial use dating back to ancient times, these remarkable organisms are now a focal point in our research from Western Ghats region to combat drug-resistant pathogens.

耐药病原体的蔓延已成为全球亟待应对的重大公共卫生挑战，亟需探寻抗菌剂的替代来源。传统抗生素的临床抗菌效力日益衰减，进一步推动了新型抗菌化合物来源的探寻工作。白蚁及其共生的白蚁巢（termitarium）凭借独特的生态互作关系与演化历程，已被证实为新型抗菌化合物的极具潜力的天然储库。这类自远古时期便展现出抗菌应用特性的非凡生物类群，如今已成为我们依托西高止山脉（Western Ghats）区域开展耐药病原体防控研究的核心焦点。