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Additional file 7: Table S6. of DNA methylation analysis of paediatric low-grade astrocytomas identifies a tumour-specific hypomethylation signature in pilocytic astrocytomas

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Figshare2016-12-14 更新2026-04-29 收录
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Three-way comparison of the test tumour set of pilocytic and diffuse astrocytomas with normal brain control tissue. 993 CpG probes are shown where the difference between the average beta values of pilocytic and diffuse astrocytomas, or between either of these and the control samples is equal to or greater than 0.3 (δβ ≥ 0.3, Benjamini-Hochberg corrected p-value <0.05), assessed by MethLAB. Illumina annotation is included. (XLSX 436 kb)

本数据集包含通过MethLAB软件完成的三组比较分析:针对毛细胞型星形细胞瘤(pilocytic astrocytomas)测试肿瘤样本集、弥散型星形细胞瘤(diffuse astrocytomas)测试肿瘤样本集与正常脑组织对照组织开展的对比分析,最终筛选出993个CpG探针(CpG probes)。上述探针满足以下条件:毛细胞型与弥散型星形细胞瘤的平均β值差值,或二者任一与对照样本的平均β值差值均≥0.3(Δβ≥0.3),且经本雅明尼-霍赫贝格(Benjamini-Hochberg)校正后的P值均小于0.05。数据集附带Illumina注释信息,文件为XLSX格式,大小436 KB。
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2016-12-14
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