Blood gas alterations in horses subjected to small colon distention

ABSTRACT The objective of this study was to evaluate the blood gas analysis of venous blood of horses with experimentally induced ischemic lesions on the lower colon. Eight healthy horses were used, with ages between five and eight years, mixed breed. The animals were subjected to celiotomy and four hours of lower colonic intraluminal obstruction. The harvests were made with the blood samples immediately before induction of anesthesia (T0), when the anesthesia was stabilized (T1), 4 hours after the intraluminal obstruction (T4) and during postsurgical times were performed at intervals of 12 hours to complete 72 hours (T16, T28, T40, T52, T64 and T76). The occurrence of metabolic alkalosis on T4 with respiratory compensation by hypoventilation was noted, this alkalosis period was bland and transient, returning the normal values for the specie on T16, 12 hours after the intestinal obstruction.

摘要 本研究旨在对实验性诱发结肠下段缺血性损伤的马匹的静脉血气分析结果进行评估。本研究选用8匹年龄介于5至8岁的混种健康马匹。受试马匹接受剖腹手术，并造成4小时的结肠下段肠腔内阻塞。血样采集分别在以下时间点完成：麻醉诱导前即刻（T0）、麻醉稳定后（T1）、肠腔内阻塞后4小时（T4），以及术后每隔12小时连续采集至72小时（分别为T16、T28、T40、T52、T64和T76）。研究观察到，在T4时间点出现代谢性碱中毒，并伴随通气不足引发的呼吸代偿；该碱中毒状态轻微且呈一过性，在肠阻塞后12小时的T16时间点，马匹血气指标恢复至该物种的正常参考范围。