ChIP-seq of H3K4me2, H3K9me2, and H3K27me3 was performed in YB5 cells to determine the impact of baseline histone methylation patterns on gene reactivation by epigenetic therapy Biological duplicates
Hypoxia-Inducible Factor 1 (HIF-1) plays a key role in cellular adaptation to hypoxia. To better understand the determinants of HIF-1 binding and transactivation, we used ChIP-chip and gene expression
The cell death protease caspase-8 plays an essential role in controlling inflammation, as severe immunodeficiency results from its loss. We previously found that caspase-8 promotes inflammatory respon
Identification of the DNA binding landscape of the transcription factor regulatory factor X 7 (RFX7) in Nutlin-3a and DMSO control treated RPE-1 cells. Overall design: RFX7 ChIP-seq in Nutlin-3a and D