QuantiFERON TB Results in Health Outcomes around Pregnancy and Exposure to HIV/ARVs

LBW0183: QuantiFERON TB Results (February 2025)
Study Description
The Health Outcomes around Pregnancy and Exposure to HIV/ARVs (HOPE) study investigates physical and mental health outcomes and health related behaviors of women living with HIV of reproductive age, including women living with HIV since birth. Health outcomes include HIV disease course, engagement in care, mental health, pregnancy, reproductive health and choices, and cardiometabolic health as well as multi-level social and structural determinants of health and sources of resilience. The framework is informed by a social ecological model, life course perspective, and community engagement. Data collection consists of clinical assessments, online surveys, health interviews, collection of specimens and medical chart abstraction designed to achieve the primary objectives and domain specific aims of the study, as outlined in the protocol. Results from HOPE aim to advance the health of women living with HIV, inform clinical guidelines and shape supportive interventions and policies that address the needs and priorities of women living with HIV and their families. HOPE includes 437 women aged 18-45 living with HIV enrolled into one of four groups: Nulliparous and non-pregnant (n=85), Pregnant or recently delivered (n=58), Postpartum and non-pregnant (n=79), or Parous and non-pregnant (n=215)

LBW0183：QuantiFERON TB检测结果（2025年2月）
研究概况
妊娠与HIV/抗反转录病毒药物（Antiretrovirals, ARVs）暴露相关健康结局（HOPE）研究旨在探究育龄HIV感染女性（包括自出生即感染HIV的女性）的身心健康结局及健康相关行为。本研究涵盖的健康结局包括HIV疾病进程、诊疗随访参与度、心理健康、妊娠情况、生殖健康与生育抉择、心血管代谢健康，以及多维度的社会与健康结构决定因素与韧性来源。本研究框架基于社会生态学模型、生命历程视角与社区参与原则构建。数据采集环节包含临床评估、线上问卷、健康访谈、标本采集与病历摘要提取，所有流程均严格按照研究方案中明确的核心目标与领域专项目标设计实施。本研究成果旨在改善HIV感染女性的健康水平，为临床指南制定提供科学依据，并优化针对性支持性干预措施与政策，以满足HIV感染女性及其家庭的需求与优先事项。本研究共纳入437名年龄在18至45岁之间的HIV感染女性，分为四组：未产且未妊娠组（n=85）、妊娠或近期分娩组（n=58）、产后非妊娠组（n=79）以及经产且非妊娠组（n=215）