Drug-induced sleep endoscopy in the identification of obstruction sites in patients with obstructive sleep apnea: a systematic review

INTRODUCTION: Obstructive sleep apnea syndrome has multifactorial causes. Although indications for surgery are evaluated by well-known diagnostic tests in the awake state, these do not always correlate with satisfactory surgical results.OBJECTIVE: To undertake a systematic review on endoscopy during sleep, as one element of the diagnosis routine, aiming to identify upper airway obstruction sites in adult patients with OSAS.METHODS: By means of electronic databases, a systematic review was performed of studies using drug-induced sleep endoscopy to identify obstruction sites in patients with OSAS.RESULTS: Ten articles were selected that demonstrated the importance of identifying multilevel obstruction, especially in relation to retrolingual and laryngeal collapse in OSAS.CONCLUSION: DISE is an additional method to reveal obstruction sites that have not been detected in awake patients.

引言：阻塞性睡眠呼吸暂停综合征（Obstructive Sleep Apnea Syndrome，OSAS）的病因具有多源性。尽管手术指征需通过清醒状态下的常规诊断检查进行评估，但此类检查结果与理想的手术预后并不总是具有相关性。
研究目的：针对作为临床诊断常规环节之一的睡眠内镜检查开展系统综述，旨在明确成人阻塞性睡眠呼吸暂停综合征患者的上气道阻塞部位。
研究方法：通过电子数据库，对采用药物诱导睡眠内镜检查以识别阻塞性睡眠呼吸暂停综合征患者气道阻塞部位的相关研究进行系统综述。
研究结果：共纳入10篇符合标准的文献，结果证实了识别多平面气道阻塞的重要性，尤其针对阻塞性睡眠呼吸暂停综合征患者的舌后区及喉腔塌陷情况。
结论：药物诱导睡眠内镜（Drug-induced Sleep Endoscopy，DISE）是一种可用于检出清醒状态下未被发现的气道阻塞部位的补充诊断手段。