miR-195-5p Regulates Hair Follicle Inductivity of Dermal Papilla Cells by Suppressing Wnt/β-catenin Activation. Homo sapiens

We performed microarray analysis to detect the differential expression of miRNAs in early- vs. late-passage DP cells by microarray profiling of the total of 1924 hsa-miRNAs (miRNAs) Overall design: In the study presented here, the human scalp specimens were obtained from selected face-lift surgeries of healthy patients . We randomly select three dermal papilla cell strains to subculture and compare the differential expression of miRNAs in early- vs. late-passage DP cells by microarray analysis

本研究通过微阵列表达谱分析，对共计1924种人类微小RNA（hsa-miRNAs，以下简称miRNAs）进行检测，以分析早期传代与晚期传代的真皮乳头（dermal papilla, DP）细胞间miRNA的差异表达情况。
实验设计：本研究所使用的人类头皮标本取自健康患者的择期面部提升手术。我们随机选取3株真皮乳头细胞株进行传代培养，并通过微阵列分析比较早期与晚期传代DP细胞中miRNA的差异表达。