Associations between SNPs of MTHFR, MTR, MTRR, DNMT1, and ALDH2 genes and cancers of the esophagus, stomach, and liver.

1: Semi-Bayes odds ratio (SBOR) adjusted for age (5-year categories and deviation from stratum mean) and sex.
2: SBOR further adjusted for residency (city, rural), alcohol drinking frequency, smoking pack-years, BMI, education, H. pylori infection (in stomach cancer analyses), HBsAg (in liver cancer analyses), and plasma AFB1 levels (in liver cancer analyses), based on the assumption that genotype did not affect any of these variables.
*: One-sided semi-Bayes P-values; the posterior probability that the point estimate is on the wrong side of the null [26], [27].
†: P-value from Chi-Square test for trend.
Associations between SNPs of MTHFR, MTR, MTRR, DNMT1, and ALDH2 genes and cancers of the esophagus, stomach, and liver.

1: 半贝叶斯比值比（Semi-Bayes odds ratio, SBOR）已针对年龄（按5年分组并减去层均值）及性别进行校正。
2: 基于基因型不影响上述任一变量的假设，半贝叶斯比值比（SBOR）进一步校正了居住状况（城市、农村）、饮酒频率、吸烟包年数、体质量指数（Body Mass Index, BMI）、教育程度、幽门螺杆菌（Helicobacter pylori, H. pylori）感染（胃癌分析中）、乙型肝炎表面抗原（Hepatitis B surface antigen, HBsAg）（肝癌分析中）及血浆黄曲霉毒素B1（Aflatoxin B1, AFB1）水平（肝癌分析中）。
*: 单侧半贝叶斯P值：即点估计值落在无效假设另一侧的后验概率[26], [27]。
†: 趋势卡方检验的P值。
MTHFR、MTR、MTRR、DNMT1及ALDH2基因的单核苷酸多态性（Single Nucleotide Polymorphisms, SNPs）与食管癌、胃癌及肝癌的关联。