Variance of cerebellar probe expression levels due to technical, biological, and <i>cis</i>SNP effects.

Results from some of the top probes are depicted. Only one probe is selected per gene for depiction. R2technical = variance due to technical variables only (i.e. plates, RIN). addR2covariates = added proportion of variance due to biological covariates (i.e. age, sex, ApoE4 dose), adjR2covariates = addR2covariates adjusted for technical variance, addR2best-SNP = proportion of variance due to the best cisSNP, adjR2best-SNP = addR2best-SNP adjusted for technical variance.本数据集展示了部分优质探针（probe）的检测结果，每个基因仅选取一枚探针用于可视化呈现。R2technical：仅由技术变量（如实验板、RNA完整性数RIN）所贡献的方差；addR2covariates：由生物学协变量（如年龄、性别、载脂蛋白E4（ApoE4）剂量）额外贡献的方差占比；adjR2covariates：针对技术方差对addR2covariates进行校正后的结果；addR2best-SNP：由最优顺式SNP（cisSNP）所贡献的方差占比；adjR2best-SNP：针对技术方差对addR2best-SNP进行校正后的结果。