The Genome-wide Signature of Short-term Temporal Selection. Daphnia pulex strain:PA

Genome-wide analysis of population data reveals that temporal variation in selection intensity is a major determinant of levels of nucleotide polymorphism and divergence, raising challenges for the conventional interpretation of these measures as indicators of eective population sizes and intensities of positive/negative selection.

针对群体数据开展的全基因组分析（Genome-wide analysis）表明，选择强度的时间变异是核苷酸多态性与序列分化水平的核心决定因素，这使得将上述指标作为有效种群大小（effective population size）以及正/负选择强度的传统解读方式面临挑战。