Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-783
收藏Protein Data Bank Japan2024-05-22 更新2026-03-21 收录
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Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-783 Descriptor: 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-N-(dimethylsulfamoyl)propanamide, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2021-12-20 Release date: 2022-02-09 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal Structure of Dihydrofolate Reductase from Mycobacterium tuberculosis bound to NADP and SDDC Inhibitor SDDC-783 to be published
结核分枝杆菌（Mycobacterium tuberculosis）二氢叶酸还原酶与NADP及SDDC抑制剂SDDC-783结合的晶体结构
描述：3-(2-{3-[(2,4-二氨基-6-乙基嘧啶-5-基)氧基]丙氧基}苯基)-N-(二甲基磺酰基)丙酰胺、二氢叶酸还原酶（Dihydrofolate reductase）、烟酰胺腺嘌呤二核苷酸磷酸（NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE，简称NADP）
作者：西雅图传染病结构基因组学中心（Seattle Structural Genomics Center for Infectious Disease, SSGCID）
提交日期：2021-12-20
发布日期：2022-02-09
最后修改日期：2024-05-22
研究方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.55埃
引用信息：结核分枝杆菌二氢叶酸还原酶与NADP及SDDC抑制剂SDDC-783结合的晶体结构，待发表
创建时间：
2021-12-20
