A proposal of Brazilian Society of Surgical Oncology (BSSO/SBCO) for standardizing cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) procedures in Brazil: pseudomixoma peritonei, appendiceal tumors and malignant peritoneal mesothelioma

ABSTRACT Cytoreductive surgery plus hypertermic intraperitoneal chemotherapy has emerged as a major comprehensive treatment of peritoneal malignancies and is currently the standard of care for appendiceal epithelial neoplasms and pseudomyxoma peritonei syndrome as well as malignant peritoneal mesothelioma. Unfortunately, there are some worldwide variations of the cytoreductive surgery and hypertermic intraperitoneal chemotherapy techniques since no single technique has so far demonstrated its superiority over the others. Therefore, standardization of practices might enhance better comparisons between outcomes. In these settings, the Brazilian Society of Surgical Oncology considered it important to present a proposal for standardizing cytoreductive surgery plus hypertermic intraperitoneal chemotherapy procedures in Brazil, with a special focus on producing homogeneous data for the developing Brazilian register for peritoneal surface malignancies.

摘要
肿瘤细胞减灭术（Cytoreductive Surgery）联合腹腔热灌注化疗（Hyperthermic Intraperitoneal Chemotherapy）已成为腹膜恶性肿瘤的主要综合治疗手段，目前是阑尾上皮性肿瘤、腹膜假黏液瘤综合征以及恶性腹膜间皮瘤的标准治疗方案。遗憾的是，当前全球范围内肿瘤细胞减灭术与腹腔热灌注化疗的技术仍存在差异，尚无任何一种术式被证实优于其他术式。因此，实现操作标准化或可提升不同治疗结局间的可比性。鉴于此背景，巴西外科肿瘤学会（Brazilian Society of Surgical Oncology）认为有必要提出一项针对巴西地区肿瘤细胞减灭术联合腹腔热灌注化疗操作的标准化建议，重点为开发巴西腹膜表面恶性肿瘤注册数据库提供同质化数据支撑。