Secretome containing extracellular vesicles (EV) from cardiovascular progenitors (EV-CPC) vs the secretome containing EV from Fibroblasts (EV-FB)

Secretome containing extracellular vesicles (EV) seem to mediate the benefits of cell therapy for ischemic heart failure. Our project has the objective of comparing the secretome containing extracellular vesicles (EV) from cardiac progenitor cells (EV-CPC) vs the secretome containing EV from Fibroblasts (EV-FB) in order to stablish a protein cartography of EV-CPC and the biological pathways that they are involved. seem to mediate the benefits of cell therapy for ischemic heart failure. Our project has the objective of comparing the secretome containing extracellular vesicles (EV) from cardiac progenitor cells (EV-CPC) vs the secretome containing EV from Fibroblasts (EV-FB) in order to stablish a protein cartography of EV-CPC and the biological pathways that they are involved.

含细胞外囊泡（extracellular vesicles, EV）的分泌组似乎可介导缺血性心力衰竭细胞疗法的获益。本项目旨在对比源自心脏祖细胞（cardiac progenitor cells, CPC）的含EV分泌组（EV-CPC）与成纤维细胞（fibroblasts）来源的含EV分泌组（EV-FB），以绘制EV-CPC的蛋白质图谱及其参与的生物学通路。