Optic coherence tomography measurement of choroidal and retinal thicknesses after uncomplicated YAG laser capsulotomy

ABSTRACT Purpose: Optic coherence tomography (OCT) evaluation of the choroid, retina, and retinal nerve fiber layer after uncomplicated yttrium-aluminum-garnet (YAG) laser capsulotomy. Methods: OCT analysis of retinal and choroidal structures was performed in 28 eyes of 28 patients following routine examinations before and 24 h, 72 h, 2 weeks, 4 weeks, and 12 weeks after YAG laser capsulotomy. Data were analyzed using the SPSS software. Results: Data collected before YAG capsulotomy and at the above mentioned follow-up visits are summarized as follows. Mean central subfoveal choroidal thickness before YAG capsulotomy was 275.85 ± 74.78 µm; it was 278.46 ± 83.46 µm, 283.39 ± 82.84 µm, 280.00 ± 77.16 µm, 278.37 ± 76.95 µm, and 278.67 ± 76.20 µm after YAG capsulotomy, respectively. Central macular thickness was 272.14 ± 25.76 µm before YAG capsulotomy; it was 266.53 ± 26.47 µm, 269.14 ± 27.20 µm, 272.17 ± 26.97 µm, 270.91 ± 26.79 µm, and 273 ± 26.63 µm after YAG capsulotomy, respectively. Mean retinal nerve fiber layer thickness before YAG was 99.89 ± 7.61 µm; it was 98.50 ± 8.62 µm, 98.14 ± 8.69 µm, 99.60 ± 8.39 µm, 99.60 ± 8.39 µm, and 99.60 ± 8.35 µm after YAG capsulotomy, respectively. No observed change was statistically significant. No significant changes were observed with regard to mean intraocular pressure. Conclusions: After YAG laser capsulotomy, no statistically significant changes were found in choroidal, retinal, and optical nerve fiber layer thicknesses, although slight thickness changes in these structures were observed, particularly during the first days.

摘要
研究目的：评估无并发症钇铝石榴石（yttrium-aluminum-garnet，YAG）激光囊膜切开术后患者的脉络膜、视网膜及视网膜神经纤维层的光学相干断层扫描（Optic coherence tomography，OCT）表现。
研究方法：对28例患者共28只眼，在YAG激光囊膜切开术前常规检查时，以及术后24h、72h、2周、4周、12周时分别开展视网膜与脉络膜结构的光学相干断层扫描分析，采用SPSS软件对采集的数据进行统计处理。
研究结果：将术前及上述随访时间点的收集数据总结如下。YAG激光囊膜切开术前，中心凹下脉络膜平均厚度为275.85±74.78μm；术后各随访时间点对应的平均厚度分别为278.46±83.46μm、283.39±82.84μm、280.00±77.16μm、278.37±76.95μm及278.67±76.20μm。中心黄斑厚度术前为272.14±25.76μm，术后各时间点分别为266.53±26.47μm、269.14±27.20μm、272.17±26.97μm、270.91±26.79μm及273±26.63μm。术前视网膜神经纤维层平均厚度为99.89±7.61μm，术后各时间点分别为98.50±8.62μm、98.14±8.69μm、99.60±8.39μm、99.60±8.39μm及99.60±8.35μm。所有观测变化均无统计学意义。平均眼压亦未出现显著改变。
研究结论：YAG激光囊膜切开术后，尽管在术后早期可观察到上述结构存在轻微的厚度变化，但脉络膜、视网膜及视网膜神经纤维层厚度均未出现具有统计学意义的显著改变。