Additional file 2 of Human cell-dependent, directional, time-dependent changes in the mono- and oligonucleotide compositions of SARS-CoV-2 genomes

Additional file 2: Table S1. List of SARS-CoV-2 strains used in the analysis. Table S2. List of human-and bat-CoV strains used in the analysis. Table S3. Number of SARS-CoV-2 strains in each clade isolated in each elapsed month. Table S4. Average oligonucleotide compositions for SARS-CoV-2 strains in each clade isolated in each elapsed month. Table S5. Correlation coefficients for time-dependent changes in oligonucleotide compositions of SARS-CoV-2. Table S6. Fold change in compositions between strains of the first and last month of the analysis. Table S7. Distance between the oligonucleotide composition of SARS-CoV-2 isolated in each elapsed month and that of human-CoV. Table S8. Correlation coefficients for time-series changes in the distance between oligonucleotide compositions of SARS-CoV-2 and human-CoV. Table S9. List of RNA-binding motifs. Table S10. Numbers of motif-containing loci for RNA-binding proteins whose abundance increases or decreases between strains of the first and last month of the analysis. Table S11. P-value from t-test to analyze the number of RNA-binding motif loci whose abundance increases or decreases between strains of the first and last month of the analysis. Table S12. Correlation coefficients for time-dependent changes in the number of loci containing RNA-binding motifs.

附加文件2：表S1 本分析所用新型冠状病毒（SARS-CoV-2）毒株列表。
表S2 本分析所用人类冠状病毒（human-CoV）及蝙蝠冠状病毒（bat-CoV）毒株列表。
表S3 各时段分离的各进化枝新型冠状病毒毒株数量。
表S4 各时段分离的各进化枝新型冠状病毒毒株的寡核苷酸组成平均值。
表S5 新型冠状病毒寡核苷酸组成随时间变化的相关系数。
表S6 分析时段首月与末月毒株间的组成差异倍数。
表S7 各时段分离的新型冠状病毒与人类冠状病毒（human-CoV）的寡核苷酸组成差异距离。
表S8 新型冠状病毒与人类冠状病毒寡核苷酸组成差异随时间序列变化的相关系数。
表S9 RNA结合基序（RNA-binding motifs）列表。
表S10 分析时段首月与末月毒株间丰度发生升降的RNA结合蛋白的含基序位点数量。
表S11 针对分析时段首月与末月毒株间丰度增减的RNA结合基序位点数量进行t检验所得的P值。
表S12 含RNA结合基序的位点数量随时间变化的相关系数。