Crystal structure of compound 8t bound to PaLpxC
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Crystal structure of compound 8t bound to PaLpxC Descriptor: 1-{(2S)-3-(5-hydroxy-6-oxo-1,6-dihydropyrimidin-4-yl)-2-[4-({4-[(morpholin-4-yl)methyl]phenyl}ethynyl)phenyl]propyl}azetidine-3-carbonitrile, SULFATE ION, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... Authors: Martin, D.P. Deposit date: 2026-02-04 Release date: 2026-08-19 Last modified: 2026-08-26 Method: X-RAY DIFFRACTION (1.902 Å) Cite: Discovery and Optimization of Novel Nonhydroxamate LpxC Inhibitors for the Treatment of Multidrug-Resistant Gram-Negative Infections. J.Med.Chem., 69, 2026
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2026-02-04
