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For Dan Found all the data for the graph.xlsx from Gestational growth trajectories derived from a dynamic fetal–placental scaling law

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The Royal Society Figshare2019-10-30 更新2026-04-17 收录
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https://rs.figshare.com/articles/For_Dan_Found_all_the_data_for_the_graph_xlsx_from_Gestational_growth_trajectories_derived_from_a_dynamic_fetal_placental_scaling_law/10047371/1
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资源简介:
Fetal trajectories characterizing growth rates <i>in utero</i> have relied primarily on goodness of fit rather than mechanistic properties exhibited <i>in utero</i>. Here, we use a validated fetal–placental allometric scaling law and a first principles differential equations model of placental volume growth to generate biologically meaningful fetal–placental growth curves. The growth curves form the foundation for understanding healthy versus at-risk fetal growth and for identifying the timing of key events <i>in utero</i>.

表征子宫内(in utero)胎儿生长速率的轨迹,既往研究多以拟合优度为核心依据,而非基于子宫内所展现的生物学机制特性。本研究采用经验证的胎儿-胎盘异速标度律(allometric scaling law),以及基于第一性原理的胎盘体积生长微分方程模型,生成了具备明确生物学意义的胎儿-胎盘生长曲线。此类生长曲线可为区分健康与高危胎儿生长状态,以及识别子宫内关键事件的发生时机提供核心研究基础。
提供机构:
Ruchit Shah
创建时间:
2019-10-25
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