Microbiome permissivity to Blautia colonisation during recovery from chronic broad-spectrum antibiotic administration is dependent on dietary fibres in adult male rats.

In adult male rats, we sought to characterise the effects of prebiotics, faecal microbiota transfer and natural recolonisation on the gut microbiota after 4-week administration of a cocktail of antibiotics or vehicle. 16S sequencing of the caecal contents was performed for microbiota analysis.

本研究以成年雄性大鼠为实验对象，旨在阐明经4周抗生素联合制剂或赋形剂给药后，益生元（prebiotics）、粪便菌群移植（faecal microbiota transfer）及自然菌群再定植对肠道菌群的调控效应。本研究通过对盲肠内容物进行16S测序（16S sequencing）以开展菌群组成分析。