Improvement of isopropanol tolerance of Escherichia coli using adaptive laboratory evolution and omics technology. Escherichia coli str. K-12 substr. MDS42

To understand the mechanism of isopropanol tolerance of Escherichia coli for improvement of isopropanol production, we performed genome re-sequencing analysis of isopropanol tolerant E. coli strains obtained from parallel adaptive laboratory evolution under IPA stress.

为阐明大肠杆菌（Escherichia coli）的异丙醇耐受机制以提升异丙醇产量，我们对在异丙醇（IPA）胁迫下通过平行适应性实验室进化获得的异丙醇耐受大肠杆菌菌株进行了基因组重测序分析。