Oral infection by Pseudomonas aeruginosa in patient with chronic kidney disease - a case report

ABSTRACT Chronic renal patients are more susceptible to hospital complications and infections such as urinary tract infections, peritonitis, surgery infections, and bacteremia, which are often caused by Pseudomonas aeruginosa. A case of a HIV-positive girl with chronic kidney disease and with serious oral lesions due to P. aeruginosa septic shock is presented. The patient showed necrotic lesions in the oral mucosa, pathological tooth mobility, bone loss, and hematogenous osteomyelitis in the maxilla. The patient was submitted to systemic antibiotic therapy based on screening culture and treatment of bone lesions by eliminating the causal agent and restoring health conditions. This case report is extremely important for health professionals, since the oral cavity can be affected by this pathogen or serve as a colonization site.

摘要：慢性肾病患者更易罹患医院获得性并发症及感染，例如尿路感染、腹膜炎、手术部位感染与菌血症，此类感染多由铜绿假单胞菌（Pseudomonas aeruginosa）引发。本文报告1例HIV阳性女童病例，该患儿罹患慢性肾病，且因铜绿假单胞菌脓毒性休克出现严重口腔病变。该患者表现出口腔黏膜坏死性病变、病理性牙松动、骨丢失及上颌骨血源性骨髓炎。患者接受基于病原筛查培养结果的全身抗生素治疗，并通过清除病原体、恢复机体健康状态来处置骨组织病变。本病例报告对医疗从业者具有重要参考价值，口腔既可被该病原体侵袭，也可作为其定植位点。