Sedation related data for children of different age groups

<b>Importance: </b>Pediatric sedation is crucial for diagnostic and therapeutic procedures, with varying impacts and risks according to age, necessitating the recognition of these differences to improve safety and efficacy.<b>Objective: </b>To investigate whether age affects the occurrence of adverse events in sedated children, focusing on critical events such as respiratory depression, delayed resuscitation, and hypoglycemia.<b>Design: </b>This research represents a retrospective cohort study gathered pertinent data between March 2022 and March 2024.<b>Setting: </b>Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, China.<b>Participants: </b>Children aged 0 to 12 years classified as ASA grade I–II, with complete medical records.<b>Intervention:</b> Participants were categorized into three age groups: ≤1, 1–3, and 3–12 years.<b>Main Outcome(s) and Measure(s): </b>The primary outcome was adverse event incidence, which was analyzed using chi-square tests and multivariate logistic regression. The sedation effect was evaluated using the rank-sum test.

<b>研究意义：</b>儿童镇静对诊断与治疗操作至关重要，其影响与风险随年龄存在差异，因此需明确这类年龄差异以提升操作安全性与有效性。<b>研究目的：</b>本研究旨在探讨年龄是否会影响接受镇静治疗的儿童不良事件的发生情况，重点关注呼吸抑制、复苏延迟及低血糖等严重不良事件。<b>研究设计：</b>本研究为回顾性队列研究，数据收集时段为2022年3月至2024年3月。<b>研究机构：</b>中国广西壮族自治区妇幼保健院。<b>研究对象：</b>年龄0~12岁，美国麻醉医师协会（ASA）分级为I~II级，且拥有完整病历资料的儿童。<b>分组方式：</b>将研究对象按年龄分为三组：≤1岁、1~3岁及3~12岁。<b>主要结局与指标：</b>本研究的主要结局为不良事件发生率，采用卡方检验及多因素logistic回归进行分析；镇静效果则采用秩和检验进行评估。