data - fQRS complex in patients with ICD

This data relates to the original research "Fragmented QRS complex in patients with ICD". Abstract Background. Incidence of fragmented (fQRS) and predisposing factors in patients with implantable cardioverter-defibrillator (ICD) have not yet been established. Aim. To examine incidence of fQRS, associated factors as well as predictive value in identifying site of coronary artery disease (CAD). Methods. Consecutive patients with ICD. Retrospective analysis of demographic, clinical and ECG data. Results. Of 382 patients, 163 (43%) had fQRS. They had more frequently history of MI, Q wave, lower left ventricular ejection fraction and prolonged ECG repolarisation indices. The presence of fQRS in more than one ECG localisation was associated with higher number of MI and ICD for secondary prevention. By combining fQRS with Q wave location, site of CAD could be predicted (total accuracy 84-95%). Conclusions. The fQRS is frequent in patients with ICD, especially those with CAD, more advanced cardiac disease and altered ECG repolarisation. The fQRS may improve ECG-based non-invasive identification of the site of CAD.

本数据关联于原创研究《植入式心脏复律除颤器（ICD）患者的碎裂QRS波》。
摘要 背景：植入式心脏复律除颤器（implantable cardioverter-defibrillator, ICD）患者中碎裂QRS波（fragmented QRS complex, fQRS）的发生率及其易感危险因素尚未明确。
研究目的：明确碎裂QRS波的发生率、相关影响因素，以及其在识别冠状动脉疾病（coronary artery disease, CAD）病灶部位中的预测价值。
研究方法：纳入连续收治的ICD置入患者，对其人口统计学资料、临床数据及心电图（electrocardiogram, ECG）数据开展回顾性分析。
研究结果：纳入的382例患者中，163例（43%）存在碎裂QRS波。此类患者更常合并心肌梗死（myocardial infarction, MI）病史、Q波，左心室射血分数更低，且心电图复极指标延长。当碎裂QRS波出现在多个心电图导联定位区域时，与更高频次的心肌梗死事件以及用于二级预防的ICD置入显著相关。将碎裂QRS波与Q波定位相结合，可实现冠状动脉疾病病灶部位的预测（总体准确率达84%~95%）。
研究结论：碎裂QRS波在ICD置入患者中较为常见，尤其多见于合并冠状动脉疾病、病情更严重的心脏疾病以及存在心电图复极异常的患者。碎裂QRS波可提升基于心电图的无创性冠状动脉疾病病灶部位识别效能。