SH1410090.10FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

UNITE 为界定、识别、交流以及开展基于DNA的物种假说（Species Hypotheses，SH）的相关工作提供了统一方法。国际核酸序列数据库中的所有真菌内转录间隔区（Internal Transcribed Spacer，ITS）序列，均通过应用一系列动态距离阈值（0.5%~3.0%）被聚类至近似物种水平。所有物种假说均被赋予以数字对象唯一标识符（Digital Object Identifier，DOI）为形式的唯一且稳定的名称，其分类学与生态学注释将通过分布式网络第三方注释工作完成验证。系统将尽可能结合某一物种假说包含的所有序列的鉴定结果，将该假说关联至对应的分类单元名称及其所属的分类层级（如门、纲、目等）。将为每一类物种假说选取一条经自动或人工指定的代表序列。这些序列已发布于https://unite.ut.ee/repository.php，可供科研界用于本地序列相似性搜索、高通量测序分析流程等科研场景。随着公共真菌ITS序列库的规模持续增长，该系统与配套数据将自动完成更新。