Hypoxia and lactate influence VOC production in A549 lung cancer cells. Hypoxia and lactate influence VOC production in A549 lung cancer cells

Investigating certain gene expressions in the VOC pathway and in lactate signaling, parallel to VOC production. Overall design: RNAseq was conducted to find out transcriptional change related to VOC increase under hypoxia, glucose change as well as lactate addition.

本研究在挥发性有机化合物（Volatile Organic Compounds，VOC）生成过程中，同步探究其通路及乳酸信号通路中的部分基因表达情况。实验设计概况：采用RNA测序（RNA-seq）技术，旨在鉴定低氧环境、葡萄糖浓度改变以及添加乳酸条件下，与VOC生成增加相关的转录变化。