Rhodopsin photocascade

This LaTeX document generates a figure of the conformational changes in Rhodopsin following absorption of a photon(hV). Following absorption of light, the 11-cis-retinal chromophore isomerizes to the all-trans configuration within 200 fs and then relaxes thermally through a series of spectrally well-defined intermediates to the active Meta II state, which binds and activates the G protein transducin. Hydrolysis of the Schiffs base linkage generates opsin and frees all-trans retinal. BSI blue light sensitive intermediate. Adapted from Smith (2010)

本LaTeX文档绘制了视紫红质（Rhodopsin）吸收光子（hV）后的构象变化示意图。光线被吸收后，11-顺式视黄醛生色团（11-cis-retinal chromophore）会在200飞秒内异构化为全反式构型，随后通过一系列光谱可分辨的中间体发生热弛豫，最终转变为具有活性的Meta II态，该状态可结合并激活G蛋白转导蛋白（transducin）。希夫碱键的水解会生成视蛋白（opsin）并释放全反式视黄醛。BSI为蓝光敏感中间体。本图改编自Smith（2010）。