Identification and Characterization of Eleven Novel Human Gamma-Papillomavirus Isolates from Healthy Skin, Found at Low Frequency in a Normal Population

Eleven novel human papillomavirus (HPV) types were isolated and characterized from healthy individuals in China. HPV163 belongs to the γ-1 species, HPV 164 and HPV 168 fit in the γ-8 species, HPV 165 and KC5 belongs to the γ-12 species, HPV 168 is closely allied with the γ-4 species, HPV 169 is closely related to the γ-11 species, and HPV 170 is related to the γ-12 species. In addition, HPV 161, HPV 162, and HPV 166 may form a new HPV species of the γ-PV genus. The prevalence of these HPV types in the normal population is low.

从中国健康个体中分离并鉴定出11种新型人乳头瘤病毒（human papillomavirus，HPV）分型。其中，HPV163隶属于γ-1种；HPV164与HPV168归属于γ-8种；HPV165与KC5隶属于γ-12种；HPV168与γ-4种亲缘关系密切；HPV169与γ-11种亲缘关系相近；HPV170与γ-12种相关。此外，HPV161、HPV162与HPV166或可构成γ-PV属内的一个新型HPV种。上述HPV分型在正常人群中的感染率较低。