Double-stranded microRNA mimics can induce length- and passenger strand-dependent effects in a cell type-specific manner (RNA 2015), Exp 2. Homo sapiens

Experiment 2 - MiRNA mimics have a length and passenger strand specific effect Wildtype and mutant variants of miR-155 and negative control miRNA mimics were transfected to address the phenotype Overall design: Cells were transfected with mimics and samples were collected in duplicate (except 23mer miR-155 wild type mimic and 23mer negative control mimic)

实验2：miRNA模拟物（miRNA mimics）的作用具有长度与乘客链特异性。本实验转染miR-155的野生型及突变型变体与阴性对照miRNA模拟物，以探究其表型效应。实验总体设计：采用各类模拟物转染细胞，除23聚体miR-155野生型模拟物组与23聚体阴性对照模拟物组外，其余各组样本均收取双份。