Pnacreatic Endocrine Development scRNAseq AnnData

Data from `Bastidas-Ponce et al. (2019) https://doi.org/10.1242/dev.173849. Pancreatic epithelial and Ngn3-Venus fusion (NVF) cells during secondary transition with transcriptome profiles sampled from embryonic day 15.5. Endocrine cells are derived from endocrine progenitors located in the pancreatic epithelium. Endocrine commitment terminates in four major fates: glucagon- producing α-cells, insulin-producing β-cells, somatostatin-producing δ-cells and ghrelin-producing ε-cells.

本数据集源自Bastidas-Ponce等（2019）的研究，原文DOI：10.1242/dev.173849。数据集包含采集自胚胎第15.5天（E15.5）、处于发育二次过渡阶段的胰腺上皮细胞与Ngn3-Venus融合（Ngn3-Venus fusion, NVF）细胞的转录组谱。内分泌细胞起源于胰腺上皮内的内分泌祖细胞，其命运定向最终分化为四种主要细胞类型：分泌胰高血糖素的α细胞、分泌胰岛素的β细胞、分泌生长抑素的δ细胞以及分泌饥饿激素的ε细胞。