Additional file 1: of Association between the insulin-like growth factor 1 gene rs2195239 and rs2162679 polymorphisms and cancer risk: a meta-analysis

Table S1. Quality score assessment. Table S2. Sensitivity analyses for rs2195239 and rs2162679 polymorphisms and cancer risk. Table S3. MAFs of rs2195239 (genomic position: chromosome12: 102462924) and rs2162679 (genomic position: Chromosome12: 102477481) and polymorphisms in the populations from the 1000 Genomes Project Phase 3. Table S4. Meta-analysis of the association between rs2195239 polymorphism and cancer risk, omitting the study of Patel or Birmann. Table S5. The OMIM numbers for important genes and pathogenic conditions in this study. Figure S1. Linkage disequilibrium analyses for IGF1 rs2195239 and rs2162679 polymorphisms in populations from the 1000 Genomes Project Phase 3. (ZIP 1155 kb)

附表S1. 质量评分评估。
附表S2. 针对rs2195239与rs2162679多态性及癌症风险的敏感性分析。
附表S3. 1000基因组计划第三阶段（1000 Genomes Project Phase 3）人群中rs2195239（基因组位置：12号染色体：102462924）与rs2162679（基因组位置：12号染色体：102477481）的次要等位基因频率（minor allele frequency, MAF）及该人群中的相关多态性。
附表S4. 剔除Patel或Birmann的研究后，rs2195239多态性与癌症风险关联的荟萃分析。
附表S5. 本研究涉及的重要基因与致病表型的OMIM（在线人类孟德尔遗传数据库，Online Mendelian Inheritance in Man）编号。
图S1. 1000基因组计划第三阶段人群中IGF1（胰岛素样生长因子1，Insulin-like Growth Factor 1）基因rs2195239与rs2162679多态性的连锁不平衡分析（ZIP 1155 kb）