Crystallographic structure of MazF-E24A toxin bound to SamF

Crystallographic structure of MazF-E24A toxin bound to SamF Descriptor: Endoribonuclease toxin MazF, SODIUM ION, peptide SER-HIS-LEU-PHE-TRP-ALA-GLN-PHE-ASP-GLU-TYR-PHE Authors: Pizzolato-Cezar, L.R, Nascimento, A.F.Z, Machini, M.T, Salinas, R.K. Deposit date: 2025-07-17 Release date: 2025-10-29 Last modified: 2025-11-05 Method: X-RAY DIFFRACTION (1.52 Å) Cite: Development of a Potent and Functional In Vivo Peptide Competitive Inhibitor for the Toxin MazF. J.Med.Chem., 68, 2025

结合SamF的MazF-E24A毒素的晶体结构。描述项：核糖核酸内切酶（Endoribonuclease）毒素MazF、钠离子、肽段SER-HIS-LEU-PHE-TRP-ALA-GLN-PHE-ASP-GLU-TYR-PHE。作者：Pizzolato-Cezar L.R、Nascimento A.F.Z、Machini M.T、Salinas R.K。提交日期：2025-07-17；发布日期：2025-10-29；最后更新日期：2025-11-05。实验方法：X射线衍射（分辨率1.52埃）。引用文献：《针对毒素MazF的强效功能性体内肽类竞争性抑制剂的开发》，《药物化学杂志》（J.Med.Chem.），2025年，第68卷。