The tolerance mechanism of diarrhetic shellfish toxins mediated by the extracellular regulated protein kinase (ERK) pathway in the mussel Perna viridis

This submission contains raw transcriptomic sequencing data from Perna viridis exposed to diarrhetic shellfish toxins (DSTs)-producing dinoflagellate (Prorocentrum lima) with ERK inhibitor PD98059. The study aimed to investigate the DSTs tolerance mechanisms mediated by ERK in bivalves. Total RNA was extracted from digestive glands using RNAisoPlus (Takara, Japan). De novo sequencing was performed in the MGI sequencer. These data will facilitate further analysis of differential gene expression and metabolic pathway regulation in response to DSTs exposure.

本次提交的数据集包含经产腹泻性贝类毒素（diarrhetic shellfish toxins，DSTs）的甲藻（dinoflagellate）利马原甲藻（Prorocentrum lima）处理，且施加细胞外调节蛋白激酶（ERK）抑制剂PD98059的翡翠贻贝（Perna viridis）的原始转录组测序数据。本研究旨在探究双壳类动物中ERK介导的腹泻性贝类毒素耐受机制。研究人员采用RNAisoPlus（日本Takara）从消化腺中提取总RNA，并使用MGI测序仪完成了从头测序（de novo sequencing）。本数据集将为后续开展腹泻性贝类毒素暴露下的差异基因表达分析及代谢通路调控研究提供有力支撑。