RNA-seq of E18.5, C57BL6 mouse retinal cells treated with glucose starvation compared with untreated controls. RNA-seq of E18.5, C57BL6 mouse retinal cells treated with glucose starvation compared with untreated controls

The experiment was performed to investigate the effects of short-term glucose starvation on the transcriptome of embryonic retinal cells. Perinatal exposure to starvation is a risk factor for development of severe retinopathy in adult patients with diabetes. Underlying molecular mechanisms were investigated via this experimental design by looking into transcriptomic changes.

本实验旨在探究短期葡萄糖饥饿对胚胎视网膜细胞转录组的影响。围产期饥饿暴露是糖尿病成年患者罹患重度视网膜病变的风险因素。本实验通过分析转录组变化，对该过程的潜在分子机制展开研究。