nuMoM2b Fetal Biometry Visit 3 [U3A] Dataset in Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be

Data from Fetal Biometry Visit 3 [U3A] form capturing results from fetal biometry performed at Visit 3 (22-29 weeks project estimated gestational age) obtained through a clinical or research ultrasound conducted by a certified sonographer
Study Description
NuMoM2b studied underlying, interrelated, mechanisms of adverse pregnancy outcomes (e.g., preterm birth, preeclampsia, fetal growth restriction) in pregnant women with no previous pregnancy lasting 20 weeks-0 days or more estimated gestational age (nulliparas). The network included 8 clinical sites, subsites, NICHD, and a data center. Women enrolled early in pregnancy and were followed through delivery, with study visits at 6 weeks-0 days to 13 weeks-6 days, 16 weeks-0 days to 21 weeks-6 days, 22 weeks-0 days to 29 weeks-6 days gestation, and delivery. Data collected through interviews, self-administered questionnaires, clinical measurements, ultrasounds, and medical records review included demographic, psychosocial, dietary, physiologic, health, and pregnancy outcome information. Subsets of participants enrolled in sleep disordered breathing, sleep patterns and quality, and fetal adrenal gland substudies. Pregnant women with no previous pregnancy lasting =20 weeks estimated gestational age (nulliparas); although 10,038 women enrolled in the study, during consent, only 9,289 of these women agreed to release their data into shared databases maintained by NIH

本数据集源自第三次胎儿生物测量访视[U3A]表单，收录了由认证超声医师通过临床或研究级超声检查获取的、项目预估孕龄为22~29周的第三次访视中的胎儿生物测量结果。
研究概况
NuMoM2b研究旨在探究既往无孕龄≥20周妊娠史的初产妇（nulliparas）发生不良妊娠结局（如早产、子痫前期、胎儿生长受限）的潜在相互关联机制。该研究网络包含8个临床中心、分中心、美国国立儿童健康与人类发育研究所（National Institute of Child Health and Human Development, NICHD）以及1个数据中心。研究人员在妊娠早期招募受试者并随访至分娩，访视节点分别为孕6周0天~13周6天、16周0天~21周6天、22周0天~29周6天，以及分娩时。研究通过访谈、自填式问卷、临床测量、超声检查及病历审查收集数据，内容涵盖人口统计学、社会心理学、膳食、生理学、健康状况及妊娠结局相关信息。部分受试者参与了睡眠呼吸障碍、睡眠模式与质量以及胎儿肾上腺亚研究。尽管本研究共招募10038名孕妇，但在知情同意阶段，仅有9289名受试者同意将其数据共享至由美国国立卫生研究院（National Institutes of Health, NIH）维护的共享数据库中。