UTX and JMDJ3 regulate NKT development

The goal of this study was to understand the transcriptional differences between UTX/JMJD3 DKO NKT precursors (P1) and WT litter mater controls. Two female and one male sample for each is included. Overall design: 6 samples, 3 WT(2F, 1M), 3 DKO (2F, 1M)

本研究旨在阐明UTX/JMJD3双敲除（double knockout, DKO）自然杀伤T细胞（Natural Killer T cell, NKT）前体细胞（P1）与野生型（Wild Type, WT）同窝对照样本之间的转录差异。两组各纳入2只雌性、1只雄性样本。整体实验设计如下：共包含6个样本，其中3份为野生型对照（2雌1雄），3份为UTX/JMJD3双敲除样本（2雌1雄）。