Salmo trutta dRAD sequencing Raw sequence reads. Salmo trutta
收藏NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA429104
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Proliferative kidney disease (PKD) is a temperature-dependent deadly disease of salmonid fishes that is caused by the myxozoan parasite Tetracapsuloides bryosalmonae. In this study, the DNA samples from the kidneys of PKD infected juveniles from a wild river population of Brown trout (Salmo trutta) have been sequenced using dRAD sequencing (PstI and BamHI restriction enzymes) approach. The aim is to identify the SNPs controlling the variation in resistance (relative parasite load) and disease symptoms(low hematocrit and kidney swollenness) in PKD infected individuals.
增殖性肾病(Proliferative kidney disease, PKD)是一种由黏孢子虫寄生虫*Tetracapsuloides bryosalmonae*引发的、依赖温度的鲑科鱼类致死性疾病。本研究采用dRAD测序(使用PstI与BamHI限制性内切酶)的方法,对野生河流种群中感染PKD的幼年褐鳟(*Salmo trutta*)的肾脏DNA样本进行了测序。本研究的目的在于鉴定调控PKD感染个体的抗性性状(相对寄生虫载量)与疾病症状(低血细胞比容及肾脏肿胀程度)变异的单核苷酸多态性(Single Nucleotide Polymorphism, SNPs)。
创建时间:
2018-01-09



