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Crystal structure of the M. abscessus LeuRS editing domain in complex with epetraborole-AMP adduct

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Protein Data Bank Japan2026-02-04 更新2026-04-19 收录
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Crystal structure of the M. abscessus LeuRS editing domain in complex with epetraborole-AMP adduct Descriptor: Leucine--tRNA ligase, SULFATE ION Authors: Kalthoff, E, Schmeing, T.M. Deposit date: 2021-05-26 Release date: 2021-10-06 Last modified: 2026-02-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline. Plos Pathog., 17, 2021

与埃普拉硼(epetraborole)-腺苷一磷酸(AMP)加合物结合的脓肿分枝杆菌(Mycobacterium abscessus, M. abscessus)亮氨酰-tRNA合成酶(LeuRS)编辑结构域的晶体结构 描述:亮氨酰-tRNA合成酶(Leucine--tRNA ligase)、硫酸根离子(SULFATE ION) 作者:Kalthoff, E.;Schmeing, T.M. 沉积日期:2021-05-26 发布日期:2021-10-06 最后修改日期:2026-02-04 实验方法:X射线衍射(2.1埃) 引用文献:埃普拉硼联合正缬氨酸可增强其对抗脓肿分枝杆菌的功效。《PLOS Pathog.》,17卷,2021年
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2021-05-26
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