HeLa transcriptome induction by IFN gamma and indoleamine 2,3-dioxygenase (IDO). Homo sapiens

We describe the modulation of gene expression by IDO induction in HeLa cells. Overall design: The RNA-seq transcriptome profile of IFN gamma-treated and IDO1-transduced HeLa cells was compared to that of untreated WT and GFP-transduced HeLa cells, respectively.

本研究阐述了海拉（HeLa）细胞中吲哚胺2,3-双加氧酶（IDO）诱导对基因表达的调控作用。实验设计概况：将经干扰素γ（IFN-γ）处理以及转染吲哚胺2,3-双加氧酶1（IDO1）的海拉细胞的RNA-seq转录组图谱，分别与未处理的野生型（WT）海拉细胞以及转染绿色荧光蛋白（GFP）的海拉细胞的转录组图谱进行对比。