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Skeletal muscle phenotype of the DE50-MD dog: picrosirius red

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https://figshare.com/articles/dataset/Skeletal_muscle_phenotype_of_the_DE50-MD_dog_picrosirius_red/20436099
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This dataset contains all picrosirius red histology data used in the manuscript    The skeletal muscle phenotype of the DE50-MD dog model of Duchenne muscular dystrophy Included are: 1) all raw images (separated by staining batch) for both longitudinal vastus lateralis and post-mortem multiple muscles (images in .tif format) These are subdivided into three .zip files for convenience (labelled appropriately) 2) quantitative 'fibrosis fraction' values derived from thos images, as per-image values and mean per-sample values, along with a sample key. This is provided as a single excel spreadsheet. All quantitative analysis used the methods described in Rapid histological quantification of muscle fibrosis and lysosomal activity using the HSB colour space https://www.biorxiv.org/content/10.1101/2022.08.02.502489v1    Also included is a data key file (excel format) containing details of every variable and sample name used in these (and other) analyses

本数据集包含本研究手稿中使用的全部天狼星红染色(picrosirius red)组织学数据。 杜兴氏肌营养不良症(Duchenne muscular dystrophy)DE50-MD犬模型的骨骼肌表型 数据集包含以下内容: 1) 所有按染色批次分组的原始图像,涵盖纵向股外侧肌样本及死后多部位肌肉样本,图像格式为.tif。为便于使用,该批图像被划分为三个已恰当命名的.zip压缩包。 2) 基于上述图像计算得到的定量纤维化分数(fibrosis fraction)数据,包含单张图像的量化值与各样本的平均值,同时附带样本对应密钥。该数据集以单个Excel电子表格形式提供。 本数据集所有定量分析均采用下述文献中记载的方法: 《基于HSB色彩空间的肌肉纤维化与溶酶体活性快速组织学定量分析》(Rapid histological quantification of muscle fibrosis and lysosomal activity using the HSB colour space) https://www.biorxiv.org/content/10.1101/2022.08.02.502489v1 此外,本数据集还附带一份数据密钥文件(Excel格式),其中详细记录了本次及其他相关分析中使用的所有变量与样本名称信息。
创建时间:
2022-08-11
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