HUH7 cells treated with gradually increasing concentrations of sorafenib for 6 months
收藏NIAID Data Ecosystem2026-05-10 收录
官方服务：
资源简介：
To explore the mechanism of sorafenib resistance.
探究索拉非尼（sorafenib）耐药机制。
应用场景：
创建时间：
2025-12-31
相关数据集
MiR-23a-3p Mediates Sorafenib Resistance in Human Hepatocellular Carcinoma: Study on The Regulatory Mechanisms and Potential Natural Suppressor from Chinese Herbal Medicine
Hepatocellular carcinoma (HCC) is the most histotye of liver cancer, which has brought great concern to global health due to the high incidence and mortality. Due to the poor diagnosis of HCC, patient
DataCite Commons2023-03-13 更新60
NEK7 induced phosphorylation of EGFR on serine 1070 drive the acquired lenvatinib resistance in hepatocellular carcinoma
NEK7 induced phosphorylation of EGFR on serine 1070 drive the acquired lenvatinib resistance in hepatocellular carcinoma
integrated proteome resources30
Genetic changes of Hep3B cells with acquired resistance to sorafenib after STIM1 knockout. Genetic changes of Hep3B cells with acquired resistance to sorafenib after STIM1 knockout
In order to explore the role of STIM1 in the acquired resistance of Hep3B cells to sorafenib, we used CRISPR Cas9 technology to knock out STIM1. Overall design: Comparative gene expression profile ana
NIAID Data Ecosystem20
The hsa_circRNA_102049 mediates the sorafenib sensitivity of hepatocellular carcinoma cells by regulating Reelin gene expression
A growing body of research has illuminated that non-coding RNAs (ncRNAs) plays an important role in the development of drug resistance in hepatocellular carcinoma (HCC) cells. The expression profiles
NIAID Data Ecosystem30
Endogenous protein S100A14 stabilizes glutaminase to render hepatocellular carcinoma resistant to sorafenib
Many cases of advanced hepatocellular carcinoma (HCC) are resistant to the widely used drug sorafenib, which worsens prognosis. While many studies have explored how acquired resistance emerges during
NIAID Data Ecosystem20
