Dupilumab, Drug Exposure

This concept set was developed by a data scientist (KH) for a study led by CHOP clinicians Dr. Jonathan Spergel and Dr. Stan Gabryszewski, to investigate dupilumab use and autoimmune diseases in patients with asthma and atopic dermatitis. The codeset is designed for use with the PEDSnet data model. Using RxNav, the RxCUI codes for the drug dupilumab and its corresponding Clinical Dose Form Group and Clinical Drug Form codes were identified. Descendant codes were subssequently obtained, not limited by vocabulary.

本概念集由数据科学家KH为CHOP临床医生Jonathan Spergel博士与Stan Gabryszewski博士主导的研究开发，旨在探究哮喘及特应性皮炎患者使用度普利尤单抗（dupilumab）与自身免疫性疾病的关联。该代码集专为适配PEDSnet数据模型而设计。依托RxNav工具，研究人员识别出了度普利尤单抗的RxCUI代码，以及其对应的临床剂型组（Clinical Dose Form Group）与临床药物剂型（Clinical Drug Form）代码。后续获取了其所有衍生代码，且未对所用词汇表作出限制。