Biochemical profile of Mangalarga Marchador mares during the last third of pregnancy, foaling and lactation

ABSTRACT: Adaptive changes in metabolism may occur under specific physiological conditions, being necessary the knowledge of the biochemical constituents that can undergo variations during the sixty days before foaling, until the first sixty days of lactation. The present study aimed to identify and evaluate the biochemical profile of Mangalarga Marchador mares during the last third of pregnancy, foaling and lactation. For this, 48 mares were used, which formed a maintenance group (MG), composed of non-pregnant mares and an experimental group, called the transition group (TG), formed by pregnant mares. Blood samples were collected at the following times: MG was evaluated in a single time (beginning of all collections); TG was evaluated in seven times [T-60, T-30, T-15 (days before foaling), T0 (first six hours after foaling), T15, T30, T60 (days after foaling)]. All animals were submitted to biochemical analysis, in which the concentrations of total calcium, chloride, phosphorus, magnesium, sodium, potassium, uric acid, creatinine, and urea were measured. The two groups differed significantly (P

摘要：机体代谢可在特定生理状态下发生适应性改变，因此有必要明确母马分娩前60天至泌乳初期60天内可能发生变化的血液生化成分。本研究旨在鉴定并评估妊娠晚期、分娩及泌乳期的曼加尔加马尔查多母马（Mangalarga Marchador）的血液生化谱。为此，本研究共纳入48匹母马，分为维持组（MG）与过渡组（TG）：维持组由未妊娠母马组成，过渡组由妊娠母马组成。采样时间设置如下：维持组仅在单次采样节点（即全部采样的起始时间）进行检测；过渡组则分7个时间节点采样检测[T-60、T-30、T-15（分娩前天数）、T0（分娩后前6小时）、T15、T30、T60（分娩后天数）]。所有受试动物均进行生化分析，检测指标包括总钙、氯离子、磷、镁、钠、钾、尿酸、肌酐及尿素浓度。两组间存在显著差异（P